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Post by geewhiz on Apr 2, 2012 17:21:18 GMT
Hi,
So I'm from the Midlands, UK, I'm 28 and have a faecal/musty/funky odour.
I was a member of the old site with the username TrueBlue, but wasn't on that much. I just come here now and again to browse around.
Two years ago I had two TMAU test, one I paid for from a clinic recommended here and the other through my GP which was at the University Hospital Coventry. Both tests showed normal results. I've tried various diets and found it hard to stick to them.
I would like to do more with my life but feel held back with the odour, it depresses me and gets me down quiet allot.
So, uhm, yeah. Hi!
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Post by tintin10 on Apr 4, 2012 21:18:16 GMT
Hey there Geewhiz, welcome aboard to the ship of lost souls that is this forum. I know what you mean about it being hard to stick to diets especially when you don't even know is it the right one for you. I got a negative result for tmau also, I think I read somewhere that the main guy whos ultimately in charge of the testing Dr Nigel manning said only a third of the tests he sees come back positive. There must be a good few disorders that are nearly identical to tmau but tmau is the only one that is capable of being medically identified.
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Post by Anon2 on Apr 5, 2012 11:05:27 GMT
One concern I have with the Sheffield testing is that they have their 'ratio' (usually described as a % elsewhere) set much higher (or lower depending on your view) than other labs and TMAU literature. This means that in other places many people might get a 'positive' whereas at Sheffield they get an OK.
Sheffield is set at 0.21 which works out around 80% Denver is set around 85% The official TMAU article on the NIH site (by Phillips & Shephard) suggests 90% I think Dr Cashman may have his set even higher (?)
If you tested at Sheffield and your ratio was between 0.1 and 0.21, I would wonder if it would be a positive elsewhere
I am not a great believer that TMAU is a problem in itself in most cases. other than being a good biomarker of FMO3 function on amines, so it is all a gray area to me anyhow. But even the TMAU testers available, they all seem to be setting their own reference ranges.
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