TMAU and Choline Load

[paige90]

Hello all. A while back ago I was tested for TMAU. I was happy with the results for awhile since it stated that I was normal. But now it's really starting to bother me that I was not instructed to do a choline load for the test. Does this mean that the results for this test are pretty much useless? I plan on getting retested soon (using a choline load), but I'm terrified at what the results will be since my current results, even without the choline load, look a little low to me. Here are the results for anyone interested:

TMA = 1.1 umole/mmolecreat
TMAO = 19.9 umole/mmole creat
%TMAO = 94.6%

and then after that, the reference ranges:

Normals (pre-choline load):
TMA = 0.12-2.10 umole/mmole creatinine
TMAO = 9.0-244 umole/mmole creatinine
%TMAO = > 85%

Can anyone clarify what they mean by saying "pre-choline load" in parentheses after "Normals"? I'm guessing that it means that these reference ranges are specifically for results that were not affected by a choline load. Now I'm just worried about how much lower the results would be with a choline load. Any insight would be GREATLY appreciated.

[paige90]

I'm a bit surprised that no one has any input on this. Did I not make any sense?

[asian]

Hi paige90. Please don't feel bad nobody put an input. You are not being ignored. We are family but I think none of the members has any background nor training to read such result. That's just it. We care about you. Let us know what the doctors say

[Sharon]

Paige, it looks like you are processing 94.6% of choline. That is a good normal number and not even borderline( 86.1- high 8o's).

Some places do a "pre-choline load" by taking a choline pill after you collect the first urine( 24 hour test). Others say you just need to do it when you have an odor??

Did you do a single urine or 24 hour? Sorry if you felt ignored but summer is almost ended. Like me I am away a lot and miss many messages.

[paige90]

Thank you much for your replies, guys. Sharon, it was just a single urine sample given right at the hospital that day, not a collection over twenty-four hours. I ate regularly, and I have always avoided many of the foods that contain high amounts of choline (I'm a very picky eater). My odor doesn't seem to get any worse when I do eat something high in choline, however. I guess I just need to test again, this time with a choline load, and see what happens.