Post by Arun Nagrath on Nov 3, 2011 19:57:09 GMT
From Archive 24/12/10
baguio
Junior Member
Join Date: Jan 2009
Posts: 22
Mebo Testing: Where to go from here....?
I have participated in the recent Mebo research testing and also had a TMAU test which proved negative. There were some slight abnomalities in the gut fermentation test - but otherwise, the rest of the tests were normal.
I'm just wondering where to go from here. Did we get enough data from the Mebo tests to draw any realistic conclusions?
Is there any sort of pattern forming?
Is it leading us toward a new set of tests?
Apologies for all the questions - but I always like to satisfy myself that I am doing everything possible to fix a problem! With that in mind, i'm not sure i've got a focus with regard to a potential solution or unraveling this problem right now.
#2
12th April 2010
mpdela
Senior Member
Join Date: Jan 2009
Location: Miami, Florida
Posts: 1,350
Blog Entries: 3
Re: Mebo Testing: Where to go from here....?
Hi baguio,
You don’t have to apologies for asking questions! It is good that we continue asking questions until we find all the answers we need to control this condition. Sorry to hear that you haven’t found potential solution or unraveling of this problem. Have you been able to at least decrease the intensity? What opinion do you have as to the cause and triggers to your problem?
Dr. Irene Gabashvili is still waiting for a few more people to participate in the study before writing her observations in a professional journal. She said she might have to ask some of the participants a few more questions to help her arrive at a hypothesis. Being that we have not done a control group to compare results with, due to cost concerns, the results can only be presented as a hypothesis to be researched further in future studies.
Based on the results of these tests, it appears that there have been two groups, those that suffer only from halitosis and those who suffer from body odor. Unfortunately, those who suffer only from halitosis seem to have only ruled out the possibility of having gut fermentation (indicative of yeast overgrowth), or elevated Indicans or D-lactate blood levels (signs of bacterial overgrowth), and show little or no significant gut permeability abnormalities. I say that it’s unfortunate because even though it is important to rule out these things, it hasn’t shed any light on what could be causing the halitosis.
For those persons suffering from body odor, there has been some common results. All have had some degree of increased gut permeability (one case only borderline tendency) along with some having gut fermentation and some with elevated Indicans and/or D-lactate levels.
Irene being the expert should be the one giving her interpretation of these results, so I will withhold from doing so. Once she does this, we hope to get guidance from her as to the direction the Study should take.
Baguio, I would very much welcome any suggestions from you or anyone else about what questions we should be addressing in MeBO’s testing focus. We most certainly don’t have all the answers or even know all the best questions to ask, so any assistance from everyone would be greatly appreciated. Unfortunately, we are limited in funds, so at least until MEBO is fully registered as a non-profit organization in the US (process currently underway), we won’t be in a position to seek grants for research, and even when we do pursue them, there are no guarantees we’ll get any soon. Meanwhile, all our testing would have to be sufferer/tester funded, so this would also be a factor to consider when structuring a study program.
I was reading through many of the posts written in this forum by Arun, Ariana, and Sharon, regarding the chemical composition of odors. Thinking of you and your concerns, I brought back to the top a very good thread entitled, ‘Methyl Mercaptan and Skatole’, that I found very interesting.
Sorry I don’t have more answers for you, but we won’t give up.
María
#3
13th April 2010
baguio
Junior Member
Join Date: Jan 2009
Posts: 22
Re: Mebo Testing: Where to go from here....?
Quote:
Originally Posted by mpdela
Sorry to hear that you haven’t found potential solution or unraveling of this problem.
Not to find the solution is not a new thing! However, I just found that I seem to have run out of leads.
Quote:
Originally Posted by mpdela
Have you been able to at least decrease the intensity? What opinion do you have as to the cause and triggers to your problem?
I'm really at a loss as regards that - other than that its systemic and that it must originate further down the digestive system...
Quote:
Originally Posted by mpdela
Dr. Irene Gabashvili is still waiting for a few more people to participate in the study before writing her observations in a professional journal. She said she might have to ask some of the participants a few more questions to help her arrive at a hypothesis.
Only too happy to assist if this proves to be necessary.
Quote:
Originally Posted by mpdela
Based on the results of these tests......unfortunately, those who suffer only from halitosis seem to have only ruled out the possibility of having gut fermentation (indicative of yeast overgrowth), or elevated Indicans or D-lactate blood levels (signs of bacterial overgrowth), and show little or no significant gut permeability abnormalities.
Irene being the expert should be the one giving her interpretation of these results, so I will withhold from doing so. Once she does this, we hope to get guidance from her as to the direction the Study should take.
Quote:
Originally Posted by mpdela
Baguio, I would very much welcome any suggestions from you or anyone else about what questions we should be addressing in MeBO’s testing focus.
I guess I find myself bang out of ideas - but the beauty of this forum is collaboration - so I suppose I just wanted to check and see what others thoughts were.
Quote:
Originally Posted by mpdela
I was reading through many of the posts written in this forum by Arun, Ariana, and Sharon, regarding the chemical composition of odors. Thinking of you and your concerns, I brought back to the top a very good thread entitled, ‘Methyl Mercaptan and Skatole’, that I found very interesting.
I will check it out, thank you María.
baguio
Junior Member
Join Date: Jan 2009
Posts: 22
Mebo Testing: Where to go from here....?
I have participated in the recent Mebo research testing and also had a TMAU test which proved negative. There were some slight abnomalities in the gut fermentation test - but otherwise, the rest of the tests were normal.
I'm just wondering where to go from here. Did we get enough data from the Mebo tests to draw any realistic conclusions?
Is there any sort of pattern forming?
Is it leading us toward a new set of tests?
Apologies for all the questions - but I always like to satisfy myself that I am doing everything possible to fix a problem! With that in mind, i'm not sure i've got a focus with regard to a potential solution or unraveling this problem right now.
#2
12th April 2010
mpdela
Senior Member
Join Date: Jan 2009
Location: Miami, Florida
Posts: 1,350
Blog Entries: 3
Re: Mebo Testing: Where to go from here....?
Hi baguio,
You don’t have to apologies for asking questions! It is good that we continue asking questions until we find all the answers we need to control this condition. Sorry to hear that you haven’t found potential solution or unraveling of this problem. Have you been able to at least decrease the intensity? What opinion do you have as to the cause and triggers to your problem?
Dr. Irene Gabashvili is still waiting for a few more people to participate in the study before writing her observations in a professional journal. She said she might have to ask some of the participants a few more questions to help her arrive at a hypothesis. Being that we have not done a control group to compare results with, due to cost concerns, the results can only be presented as a hypothesis to be researched further in future studies.
Based on the results of these tests, it appears that there have been two groups, those that suffer only from halitosis and those who suffer from body odor. Unfortunately, those who suffer only from halitosis seem to have only ruled out the possibility of having gut fermentation (indicative of yeast overgrowth), or elevated Indicans or D-lactate blood levels (signs of bacterial overgrowth), and show little or no significant gut permeability abnormalities. I say that it’s unfortunate because even though it is important to rule out these things, it hasn’t shed any light on what could be causing the halitosis.
For those persons suffering from body odor, there has been some common results. All have had some degree of increased gut permeability (one case only borderline tendency) along with some having gut fermentation and some with elevated Indicans and/or D-lactate levels.
Irene being the expert should be the one giving her interpretation of these results, so I will withhold from doing so. Once she does this, we hope to get guidance from her as to the direction the Study should take.
Baguio, I would very much welcome any suggestions from you or anyone else about what questions we should be addressing in MeBO’s testing focus. We most certainly don’t have all the answers or even know all the best questions to ask, so any assistance from everyone would be greatly appreciated. Unfortunately, we are limited in funds, so at least until MEBO is fully registered as a non-profit organization in the US (process currently underway), we won’t be in a position to seek grants for research, and even when we do pursue them, there are no guarantees we’ll get any soon. Meanwhile, all our testing would have to be sufferer/tester funded, so this would also be a factor to consider when structuring a study program.
I was reading through many of the posts written in this forum by Arun, Ariana, and Sharon, regarding the chemical composition of odors. Thinking of you and your concerns, I brought back to the top a very good thread entitled, ‘Methyl Mercaptan and Skatole’, that I found very interesting.
Sorry I don’t have more answers for you, but we won’t give up.
María
#3
13th April 2010
baguio
Junior Member
Join Date: Jan 2009
Posts: 22
Re: Mebo Testing: Where to go from here....?
Quote:
Originally Posted by mpdela
Sorry to hear that you haven’t found potential solution or unraveling of this problem.
Not to find the solution is not a new thing! However, I just found that I seem to have run out of leads.
Quote:
Originally Posted by mpdela
Have you been able to at least decrease the intensity? What opinion do you have as to the cause and triggers to your problem?
I'm really at a loss as regards that - other than that its systemic and that it must originate further down the digestive system...
Quote:
Originally Posted by mpdela
Dr. Irene Gabashvili is still waiting for a few more people to participate in the study before writing her observations in a professional journal. She said she might have to ask some of the participants a few more questions to help her arrive at a hypothesis.
Only too happy to assist if this proves to be necessary.
Quote:
Originally Posted by mpdela
Based on the results of these tests......unfortunately, those who suffer only from halitosis seem to have only ruled out the possibility of having gut fermentation (indicative of yeast overgrowth), or elevated Indicans or D-lactate blood levels (signs of bacterial overgrowth), and show little or no significant gut permeability abnormalities.
Irene being the expert should be the one giving her interpretation of these results, so I will withhold from doing so. Once she does this, we hope to get guidance from her as to the direction the Study should take.
Quote:
Originally Posted by mpdela
Baguio, I would very much welcome any suggestions from you or anyone else about what questions we should be addressing in MeBO’s testing focus.
I guess I find myself bang out of ideas - but the beauty of this forum is collaboration - so I suppose I just wanted to check and see what others thoughts were.
Quote:
Originally Posted by mpdela
I was reading through many of the posts written in this forum by Arun, Ariana, and Sharon, regarding the chemical composition of odors. Thinking of you and your concerns, I brought back to the top a very good thread entitled, ‘Methyl Mercaptan and Skatole’, that I found very interesting.
I will check it out, thank you María.